Article
High rates of phasing errors in highly polymorphic species with low levels of linkage disequilibrium.
Molecular ecology resources - 1 Jul 2016
Bukowicki Marek, Franssen Susanne U, Schlötterer Christian
Abstract excerpt
Short read sequencing of diploid individuals does not permit the direct inference of the sequence on each of the two homologous chromosomes. Although various phasing software packages exist, they were primarily tailored for and tested on human data, which differ from other species in factors that influence phasing, such as SNP density, amounts of linkage disequilibrium (LD) and sample sizes. Despite becoming...
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