Article
Synergistic action of master transcription factors controls epithelial-to-mesenchymal transition.
Nucleic acids research - 7 Apr 2016
Chang Hongyuan, Liu Yuwei, Xue Mengzhu, Liu Haiyue, Du Shaowei, Zhang Liwen, Wang Peng
Abstract excerpt
Epithelial-to-mesenchymal transition (EMT) is a complex multistep process in which phenotype switches are mediated by a network of transcription factors (TFs). Systematic characterization of all dynamic TFs controlling EMT state transitions, especially for the intermediate partial-EMT state, represents a highly relevant yet largely unexplored task. Here, we performed a computational analysis that integrated...
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