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Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer

29 Feb 2016

Abstract excerpt

The prostate gland mainly contains basal and luminal cells constructed as a pseudostratified epithelium. Annotation of prostate epithelial transcriptomes provides a foundation for discoveries that can impact disease understanding and treatment. Here we describe a genome-wide transcriptome analysis of human benign prostatic basal and luminal epithelial populations using deep RNA sequencing. Through molecular and...

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PMID: 26924072
DOI: 10.1038/ncomms10798

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