Article
The profile of selected single nucleotide polymorphisms in patients with hypertension and heart failure with preserved and mid-range ejection fraction.
Scientific reports - 21 Aug 2017
Bielecka-Dabrowa Agata, Sakowicz Agata, Pietrucha Tadeusz, Misztal Małgorzata, Chruściel Piotr, Rysz Jacek, Banach Maciej
Abstract excerpt
The study aimed to assess the clinical significance of selected single nucleotide polymorphisms (SNPs) in patients with diastolic heart failure (HF): inflammation [-174 G/C Interleukin -6 (IL-6) rs1800795, tumor necrosis factor (TNF)-608 G/A rs1800629], fibrosis [Arg25Pro transforming growth factor β (TGF β) rs1800471], endothelial function [-786 T/C nitric oxide synthase (NOS) rs2070744], glucose and lipid...
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