Article
Association between Duffy antigen receptor expression and disease severity in sickle cell disease patients.
Hematology (Amsterdam, Netherlands) - 1 Sept 2016
Farawela Hala M, El-Ghamrawy Mona, Farhan Marwa Salah, Soliman Rania, Yousry Sherif M, AbdelRahman Hala A
Abstract excerpt
OBJECTIVES: Sickle cell disease (SCD) is associated with a pro-inflammatory state, characterized by an elevated baseline leukocyte count and inflammatory cytokines. Inflammation, white blood cell (WBC) adhesion to vascular endothelium with subsequent endothelial injury, and repeated ischemia-reperfusion injury contribute to disease pathogenesis. Identification of genetic polymorphisms that may modulate disease...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
