Article
False-positive rifampin resistant results with Xpert MTB/RIF version 4 assay in clinical samples with a low bacterial load.
Diagnostic microbiology and infectious disease - 1 May 2016
Ocheretina Oksana, Byrt Erin, Mabou Marie-Marcelle, Royal-Mardi Gertrude, Merveille Yves-Mary, Rouzier Vanessa, Fitzgerald Daniel W, Pape Jean W
Abstract excerpt
We report investigation of 22 TB cases with positive Xpert MTB/RIF result for resistance to Rifampin and "Very Low" MTB detection level. Twelve cases were false positive without rpoB mutations, 2 were false-positives with a silent mutation in rpoB codon T508, and only 10 were true positives.
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