Article
Evaluation of Xpert MTB/RIF Versus AFB Smear and Culture to Identify Pulmonary Tuberculosis in Patients With Suspected Tuberculosis From Low and Higher Prevalence Settings.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 May 2016
Luetkemeyer Anne F, Firnhaber Cynthia, Kendall Michelle A, Wu Xingye, Mazurek Gerald H, Benator Debra A, Arduino Roberto, Fernandez Michel, Guy Elizabeth, Johnson Pamela, Metchock Beverly, Sattler Fred, Telzak Edward, Wang Yun F, Weiner Marc, Swindells Susan, Sanne Ian M, Havlir Diane V, Grinsztejn Beatriz, Alland David
Abstract excerpt
BACKGROUND: The Xpert MTB/RIF (Xpert) assay is a rapid nucleic acid amplification test widely used in settings of high tuberculosis prevalence to detect tuberculosis as well asrpoBmutations associated with rifampin resistance. Data are needed on the diagnostic performance of Xpert in lower-prevalence settings to inform appropriate use for both tuberculosis detection and the need for respiratory isolation....
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