Article
GeneXpert MTB/RIF Ultra performance to detect uncommon rpoB mutations in Mycobacterium tuberculosis.
BMC research notes - 14 Jul 2023
Rigouts Leen, Keysers Jelle, Rabab Reenaers, Fissette Kristina, van Deun Armand, de Jong Bouke Catherine
Abstract excerpt
OBJECTIVE: To investigate the performance of GeneXpert MTB/RIF Ultra to accurately detect rifampicin resistance for less common rpoB mutations that potentially confer phenotypic resistance, we tested 28 such Mycobacterium tuberculosis cultures with Xpert Ultra. RESULTS: They represented 22 different (combinations of) rpoB mutations. Of 28 isolates tested, one was reported by Xpert Ultra as "No rifampicin...
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