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Evaluation of the Analytical Performance of the Xpert MTB/RIF Assay

27 May 2010

Abstract excerpt

We performed the first studies of analytic sensitivity, analytic specificity, and dynamic range for the new Xpert MTB/RIF assay, a nucleic acid amplification-based diagnostic system that detects Mycobacterium tuberculosis and rifampin (RIF) resistance in under 2 h. The sensitivity of the assay was tested with 79 phylogenetically and geographically diverse M. tuberculosis isolates, including 42 drug-susceptible...

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PMID: 20504986
DOI: 10.1128/jcm.00128-10

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