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Article

Mutations in PIK3CA sensitize breast cancer cells to physiologic levels of aspirin.

Breast cancer research and treatment - 1 Feb 2016

Turturro Sanja B, Najor Matthew S, Ruby Carl E, Cobleigh Melody A, Abukhdeir Abde M

Abstract excerpt

A review of the literature finds that women diagnosed with breast cancer, who were on an aspirin regimen, experienced a decreased risk of distant metastases and death. Several recent studies have reported an improvement in overall survival in colorectal cancer patients who harbored mutations in the oncogene PIK3CA and received a daily aspirin regimen. Breast cancer patients on a daily aspirin regimen experienced...

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Share to Aspirin
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Share to Class I Phosphatidylinositol 3-Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26915040
DOI: 10.1007/s10549-016-3729-8
PMCID: PMC4788696

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutations in PIK3CA sensitize breast cancer cells to physiologic levels of aspirin.PMID 26915040Read ↗

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