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Article

Immunodominant Dengue Virus-Specific CD8+ T Cell Responses Are Associated with a Memory PD-1+ Phenotype.

Journal of virology - 1 May 2016

de Alwis Ruklanthi, Bangs Derek J, Angelo Michael A, Cerpas Cristhiam, Fernando Anira, Sidney John, Peters Bjoern, Gresh Lionel, Balmaseda Angel, de Silva Aruna D, Harris Eva, Sette Alessandro, Weiskopf Daniela

Abstract excerpt

UNLABELLED: Dengue disease is a large public health problem that mainly afflicts tropical and subtropical regions. Understanding of the correlates of protection against dengue virus (DENV) is poor and hinders the development of a successful human vaccine. The present study aims to define DENV-specific CD8(+)T cell responses in general and those of HLA alleles associated with dominant responses in particular. In...

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Identifiers

PMID: 26912627
DOI: 10.1128/JVI.02892-15
PMCID: PMC4836325

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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