Article
Does Val/Val genotype of GSTP1 enzyme affects susceptibility to colorectal cancer in Saudi Arabia?.
Neuro endocrinology letters - 1 Jan 2016
Khabaz Mohamad Nidal, Al-Maghrabi Jaudah Ahmed, Nedjadi Taoufik, Gar Mamdooh Abdullah, Bakarman Marwan, Gazzaz Zohair Jamil, Ibrahim Adel Mohammad
Abstract excerpt
OBJECTIVES: Glutathione S-transferase pi (GSTP1) is a candidate enzyme that may be involved in colorectal cancer susceptibility. Polymorphism of GSTP1 gene may cause changes in expression or structure which lead to alteration in the efficiency of catalytic function of the enzyme variants, i.e., deficient detoxification of carcinogens and consequently influences coloreActal cancer development. The present report...
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