Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gut Bacterial DNA Translocation is an Independent Risk Factor of Flare at Short Term in Patients With Crohn's Disease.

The American journal of gastroenterology - 1 Apr 2016

Gutiérrez Ana, Zapater Pedro, Juanola Oriol, Sempere Laura, García Marifé, Laveda Raquel, Martínez Antonio, Scharl Michael, González-Navajas José M, Such José, Wiest Reiner, Rogler Gerhard, Francés Rubén

Abstract excerpt

OBJECTIVES: We aimed at evaluating bacterial DNA (bactDNA) presence in blood of Crohn's disease (CD) patients in remission as an independent risk factor of flare at 6 months. METHODS: This is a prospective, multicenter study on CD patients with Crohn's disease activity index (CDAI)<150. The primary end point was time-to-relapse as evaluated by CDAI>150 in the following 6 months. BactDNA in blood, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Crohn Disease
Share to Cytokines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Bacterial

Share to Endoscopy, Gastrointestinal

Share to Nod2 Signaling Adaptor Protein

Share to Recurrence

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 26902226
DOI: 10.1038/ajg.2016.8

Genes

NOD2
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Gut Bacterial DNA Translocation is an Independent Risk Factor of Flare at Short Term in Patients With Crohn's Disease.PMID 26902226Read ↗

Genetic susceptibility to increased bacterial translocation influences the response to biological therapy in patients with Crohn's disease.Semantic proximity Read ↗

IL26 modulates cytokine response and anti-TNF consumption in Crohn's disease patients with bacterial DNA.Semantic proximity Read ↗

Antimicrobial peptide response to blood translocation of bacterial DNA in Crohn's disease is affected by NOD2/CARD15 genotype.Semantic proximity Read ↗

NOD2 polymorphism predicts response to treatment in Crohn's disease--first steps to a personalized therapy.Semantic proximity Read ↗

Clinical and Genetic Factors Impact Time to Surgical Recurrence After Ileocolectomy for Crohn's Disease.Semantic proximity Read ↗

Nucleotide-Binding Oligomerization Domain-Containing Protein 2 Variants in Patients with Spontaneous Bacterial Peritonitis.Semantic proximity Read ↗

Clinical and genetic factors associated with clinical relapse during anti-tumor necrosis factor therapy in Japanese patients with Crohn’s diseaseSemantic proximity Read ↗

Discovery of a simple two-gene expression biomarker in whole blood predictive of the need for treatment escalation in inflammatory bowel diseaseSemantic proximity Read ↗

Exploratory Study of the Effectiveness of Granulocyte and Monocyte Adsorptive Apheresis Before Initiation of Steroids in Patients with Active Ulcerative Colitis During the COVID-19 Outbreak (EXPECT Study): A Multicenter Prospective Clinical TrialSemantic proximity Read ↗

NLRP3 promoter methylation as a predictive biomarker for glucocorticoid response in patients with inflammatory bowel diseaseSemantic proximity Read ↗

Serum lipopolysaccharide-binding protein and soluble CD14 are markers of disease activity in patients with Crohn's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.