Article
Evaluation of p53 Polymorphism in Patients with Pannus-Derived Prosthetic Dysfunction.
The Journal of heart valve disease - 1 Sept 2015
Gursoy Mustafa Ozan, Karakoyun Suleyman, Kalcik Macit, Yesin Mahmut, Gunduz Sabahattin, Astarcioğlu Mehmet Ali, Oğuz Ali Emrah, Ozkan Mehmet
Abstract excerpt
BACKGROUND AND AIM OF THE STUDY: Prosthetic valve dysfunction (PVD) due to pannus formation is considered to occur due to a bioreaction to prosthetic material. The p53 gene plays a critical role in apoptosis and cell proliferation. p53 Arg72Pro polymorphism has been found to be associated with coronary stent restenosis, but has not yet been studied in prosthetic heart valve dysfunction. The study aim was to...
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