Article
Identification of novel secreted fatty acids that regulate nitrogen catabolite repression in fission yeast.
Scientific reports - 19 Feb 2016
Sun Xiaoying, Hirai Go, Ueki Masashi, Hirota Hiroshi, Wang Qianqian, Hongo Yayoi, Nakamura Takemichi, Hitora Yuki, Takahashi Hidekazu, Sodeoka Mikiko, Osada Hiroyuki, Hamamoto Makiko, Yoshida Minoru, Yashiroda Yoko
Abstract excerpt
Uptake of poor nitrogen sources such as branched-chain amino acids is repressed in the presence of high-quality nitrogen sources such as NH4(+) and glutamate (Glu), which is called nitrogen catabolite repression. Amino acid auxotrophic mutants of the fission yeast Schizosaccharomyces pombe were unable to grow on minimal medium containing NH4Cl or Glu even when adequate amounts of required amino acids were...
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