Article
The SAGA histone acetyltransferase complex regulates leucine uptake through the Agp3 permease in fission yeast.
The Journal of biological chemistry - 2 Nov 2012
Takahashi Hidekazu, Sun Xiaoying, Hamamoto Makiko, Yashiroda Yoko, Yoshida Minoru
Abstract excerpt
Metabolic responses of unicellular organisms are mostly acute, transient, and cell-autonomous. Regulation of nutrient uptake in yeast is one such rapid response. High quality nitrogen sources such as NH(4)(+) inhibit uptake of poor nitrogen sources, such as amino acids. Both transcriptional and posttranscriptional mechanisms operate in nutrient uptake regulation; however, many components of this system remain...
Topics
- Acetyltransferases
- Amino Acid Transport Systems
- Amino Acids
- Ammonium Chloride
- Biological Transport
- Culture Media
- Gene Expression Profiling
- Leucine
- Mutation
- Oligonucleotide Array Sequence Analysis
- Schizosaccharomyces
- Schizosaccharomyces pombe Proteins
- Transaminases