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Article

An Evaluation of Central Sensitization in Patients With Sickle Cell Disease.

The journal of pain - 1 May 2016

Campbell Claudia M, Moscou-Jackson Gyasi, Carroll C Patrick, Kiley Kasey, Haywood Carlton, Lanzkron Sophie, Hand Matthew, Edwards Robert R, Haythornthwaite Jennifer A

Abstract excerpt

UNLABELLED: Central sensitization (CS), nociceptive hyperexcitability known to amplify and maintain clinical pain, has been identified as a leading culprit responsible for maintaining pain in several chronic pain conditions. Recent evidence suggests that it may explain differences in the symptom experience of individuals with sickle cell disease (SCD). Quantitative sensory testing (QST) can be used to examine CS...

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Source

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Identifiers

PMID: 26892240
DOI: 10.1016/j.jpain.2016.01.475
PMCID: PMC4851873

Genes

SCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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