Article
Embryo‐fetal erythroid cell selection from celomic fluid allows earlier prenatal diagnosis of hemoglobinopathies
18 Feb 2016
Abstract excerpt
OBJECTIVE: Celocentesis, which involves aspiration of celomic fluid at 7-9 weeks' gestation, can potentially provide early prenatal diagnosis of single-gene disorders. The main barrier to wide acceptability of this technique is contamination of the sample by maternal cells. This problem can be overcome through selection of embryo-fetal erythroid precursors, which are found in celomatic fluid. METHOD: Embryo-fetal...
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