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Article

Differentially methylated genes and androgen receptor re-expression in small cell prostate carcinomas

18 Feb 2016

Abstract excerpt

Small cell prostate carcinoma (SCPC) morphology is rare at initial diagnosis but often emerges during prostate cancer progression and portends a dismal prognosis. It does not express androgen receptor (AR) or respond to hormonal therapies. Clinically applicable markers for its early detection and treatment with effective chemotherapy are needed. Our studies in patient tumor-derived xenografts (PDX) revealed that...

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Share to Cancer-related gene regulation
Share to Epigenetics and DNA Methylation
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PMID: 26890396
DOI: 10.1080/15592294.2016.1146851

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