Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The early onset of type 1 autoimmune hepatitis has a strong genetic influence: role of HLA and KIR genes.

Genes and immunity - 1 Apr 2016

Podhorzer A, Paladino N, Cuarterolo M L, Fainboim H A, Paz S, Theiler G, Capucchio M, López S I, Machicote A, Montal S, Podesta G, Fainboim L

Abstract excerpt

We have previously reported a strong association between HLA-DRB1*1301 and type 1 pediatric autoimmune hepatitis (PAH) and between HLA-DR*0405 and adult autoimmune hepatitis (AAH). Because human killer cell immunoglobulin-like receptors are known to be associated with susceptibility to autoimmune diseases, we investigated the frequencies of HLA-A, B, C, DRB1 and KIR genes in 144 type 1 PAH and 86 AAH patients,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to PAH gene

Share to Hepatitis, Autoimmune

Share to HLA Antigens

Share to Immune Cell Function and Interaction

Share to Polymorphism, Genetic

Share to Receptors, KIR

Source

Identifiers

PMID: 26890333
DOI: 10.1038/gene.2016.7

Genes

PAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The early onset of type 1 autoimmune hepatitis has a strong genetic influence: role of HLA and KIR genes.PMID 26890333Read ↗

Genetic aspects of adult and pediatric autoimmune hepatitis: A concise review.Semantic proximity Read ↗

Exploring the Role of Killer Cell Immunoglobulin-Like Receptors and Their HLA Class I Ligands in Autoimmune HepatitisSemantic proximity Read ↗

Pediatric and adult forms of type I autoimmune hepatitis in Argentina: evidence for differential genetic predisposition.Semantic proximity Read ↗

Human Leukocyte Antigen Profile Predicts Severity of Autoimmune Liver Disease in Children of European Ancestry.Semantic proximity Read ↗

Human leucocyte antigens and pediatric autoimmune liver disease: diagnosis and prognosis.Semantic proximity Read ↗

Genome-wide meta-analysis identifies susceptibility loci for autoimmune hepatitis type 1.Semantic proximity Read ↗

Autoimmune hepatitis, HLA and extended haplotypes.Semantic proximity Read ↗

Genetic risk factors for autoimmune hepatitis: implications for phenotypic heterogeneity and biomarkers for drug response.Semantic proximity Read ↗

Genome-wide association study identifies variants associated with autoimmune hepatitis type 1.Semantic proximity Read ↗

HLA-DRB1 and DQB1 alleles in Japanese type 1 autoimmune hepatitis: The predisposing role of the DR4/DR8 heterozygous genotype.Semantic proximity Read ↗

Association of HLA DRB1 Allele Profile with Pediatric Autoimmune Liver Disease in IndiaSemantic proximity Read ↗

HLA and Non-HLA gene polymorphisms in autoimmune hepatitis patients of North Indian adults.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.