Article
Association analysis of IL-17A and IL-17F polymorphisms in Chinese Han women with breast cancer.
PloS one - 1 Jan 2012
Wang Lihong, Jiang Yongdong, Zhang Youxue, Wang Yuwen, Huang Sunhui, Wang Zhihua, Tian Baoling, Yang Yue, Jiang Wei, Pang Da
Abstract excerpt
BACKGROUND: Research into the etiology of breast cancer has recently focused on the role of the immunity and inflammation. The proinflammatory cytokines IL-17A and IL-17F can mediate inflammation and cancer. To evaluate the influences of IL-17A and IL-17F gene polymorphisms on the risk of sporadic breast cancer, a case-control study was conducted in Chinese Han women. METHODOLOGY AND PRINCIPAL FINDINGS: We...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Asian People
- Breast Neoplasms
- Case-Control Studies
- China
- Female
- Gene Frequency
- Genetic Predisposition to Disease