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Article

The Attenuation Phenotype of a Ribavirin-Resistant Porcine Reproductive and Respiratory Syndrome Virus Is Maintained during Sequential Passages in Pigs.

Journal of virology - 1 May 2016

Khatun Amina, Shabir Nadeem, Seo Byoung-Joo, Kim Bum-Seok, Yoon Kyoung-Jin, Kim Won-Il

Abstract excerpt

UNLABELLED: In a previous study, ribavirin-resistant porcine reproductive and respiratory syndrome virus (PRRSV) mutants (RVRp13 and RVRp22) were selected, and their resistance against random mutation was shown in cultured cells. In the present study, these ribavirin-resistant mutants were evaluated in terms of their genetic and phenotypic stability during three pig-to-pig passages in comparison with modified...

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Identifiers

PMID: 26889041
DOI: 10.1128/JVI.02836-15
PMCID: PMC4836337

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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