Article
A web-oriented software for the optimization of pooled experiments in NGS for detection of rare mutations.
BMC research notes - 17 Feb 2016
Evangelista Daniela, Zuccaro Antonio, Lančinskas Algirdas, Žilinskas Julius, Guarracino Mario R
Abstract excerpt
BACKGROUND: The cost per patient of next generation sequencing for detection of rare mutations may be significantly reduced using pooled experiments. Recently, some techniques have been proposed for the planning of pooled experiments and for the optimal allocation of patients into pools. However, the lack of a user friendly resource for planning the design of pooled experiments forces the scientists to do...
Topics
- Algorithms
- Computational Biology
- DNA
- High-Throughput Nucleotide Sequencing
- Humans
- Internet
- Mutation
- User-Computer Interface