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Article

Long noncoding RNA <i>Chast</i> promotes cardiac remodeling

17 Feb 2016

Abstract excerpt

Recent studies highlighted long noncoding RNAs (lncRNAs) to play an important role in cardiac development. However, understanding of lncRNAs in cardiac diseases is still limited. Global lncRNA expression profiling indicated that several lncRNA transcripts are deregulated during pressure overload-induced cardiac hypertrophy in mice. Using stringent selection criteria, we identified Chast (cardiac...

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PMID: 26888430
DOI: 10.1126/scitranslmed.aaf1475

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