Article
[Association analysis of neuregulin 1 gene polymorphism with schizophrenia in Chinese Han population].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Feb 2009
Zhang Hong-xing, Li Wen-qiang, Zhang Yan, Zhao Jing-ping, Lv Lu-xian, Yang Ge
Abstract excerpt
OBJECTIVE: To investigate the association of the Neuregulin 1(NRG1) gene polymorphism with schizophrenia by analyzing allele transmission in schizophrenic parent-proband trios. METHODS: Quantitative real-time PCR was used to check the genotypes of four SNPs-rs221533(C/T), rs7820838(C/T), 433E1006(A/G) and rs3924999(C/T), located at the 5o terminus of the Nrg1 gene, in 258 Chinese Han schizophrenic parent-proband...
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