Article

Deep Mediation Analysis for Multimodal Genotype-Imaging Associations with Disease Phenotypes

2025-12-05

Abstract excerpt

Both genotype and imaging data carry entangled information about the phenotypes. Associations between genotypes and phenotypes can be manifested or absent on biomedical images. While there are abundant multimodal association studies integrating genotype and imaging data, few of them disentangle their direct and indirect effects in associations. We propose GIF (Genotype-Image-Phenotype), a novel modeling framework...

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Literature Corpus work: a029a298-3f53-5958-8c80-e9d10208e4a3
DOI: 10.64898/2025.11.20.689376

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