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Article

Utilization of excess NADH in 2,3-butanediol-deficient Klebsiella pneumoniae for 1,3-propanediol production.

Journal of applied microbiology - 1 Sept 2014

Cui Y L, Zhou J J, Gao L R, Zhu C Q, Jiang X, Fu S L, Gong H

Abstract excerpt

AIMS: To utilize excess NADH for 1,3-propanediol production by 2,3-butanediol-deficient mutants, the effect of dhaT overexpression in two distinct 2,3-butanediol-deficient mutants was investigated. METHODS AND RESULTS: Two 2,3-butanediol-deficient mutants, KG1-3 (blocking of the 2,3-butanediol pathway only) and KG1-5 (blocking of both of 2,3-butanediol and lactate pathways) were constructed. Our results showed...

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PMID: 24961176
DOI: 10.1111/jam.12588

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