Article
Proteomics of HCV virions reveals an essential role for the nucleoporin Nup98 in virus morphogenesis
16 Feb 2016
Abstract excerpt
Hepatitis C virus (HCV) is a unique enveloped virus that assembles as a hybrid lipoviral particle by tightly interacting with host lipoproteins. As a result, HCV virions display a characteristic low buoyant density and a deceiving coat, with host-derived apolipoproteins masking viral epitopes. We previously described methods to produce high-titer preparations of HCV particles with tagged envelope glycoproteins...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
