Article
Molecular evidence for the coordination of nitrogen and carbon metabolisms, revealed by a study on the transcriptional regulation of the agl3EFG operon that encodes a putative carbohydrate transporter in Streptomyces coelicolor.
Biochemical and biophysical research communications - 18 Mar 2016
Cen Xu-Feng, Wang Jing-Zhi, Zhao Guo-Ping, Wang Ying, Wang Jin
Abstract excerpt
In the agl3EFGXYZ operon (SCO7167-SCO7162, abbreviated as agl3 operon) of Streptomyces coelicolor M145, agl3EFG genes encode a putative ABC-type carbohydrate transporter. The transcription of this operon has been proved to be repressed by Agl3R (SCO7168), a neighboring GntR-family regulator, and this repression can be released by growth on poor carbon sources. Here in this study, we prove that the transcription...
Topics
- Bacterial Proteins
- Base Sequence
- Binding Sites
- Carbohydrate Metabolism
- Carbon
- Gene Expression Regulation, Bacterial
- Molecular Sequence Data
- Mutation
- Nitrogen
- Operon