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Article

Association between premature ovarian failure, polymorphisms in MTHFR and MTRR genes and serum homocysteine concentration.

Reproductive biomedicine online - 1 Apr 2016

Hou Ningning, Chen Songchang, Chen Feng, Jiang Minmin, Zhang Junyu, Yang Yanmei, Zhu Bo, Bai Xiaoxia, Hu Yuting, Huang Hefeng, Xu Chenming

Abstract excerpt

This study investigated the association between premature ovarian failure (POF), MTHFR C677T/A1298C and MTRR A66G genotypes and serum homocysteine (Hcy) concentration. A prospective study was conducted in Chinese women, which included POF patients (n = 180) and controls (n = 195). Peripheral blood samples were used to determine MTHFR C677T/A1298C and MTRR A66G genotypes, and serum Hcy and sex hormone...

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Source

Identifiers

PMID: 26874989
DOI: 10.1016/j.rbmo.2016.01.009

Genes

MTRR
MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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