Article
The relationship between the C677T polymorphism of the MTHFR gene and serum levels of luteinizing hormone in males with erectile dysfunction.
Neuro endocrinology letters - 1 Jan 2012
Šerý Omar, Šrámková Taťána, Klempová Jitka, Štastný František, Lochman Jan, Khan Naim Akhtar
Abstract excerpt
OBJECTIVES: The methylenetetrahydrofolate reductase (MTHFR) enzyme activity plays an important role in the metabolism of folate within methionine-homocysteine pathway and, consequently, in the development of vascular diseases. The C677T polymorphism (rs1801133) of the MTHFR gene affects the MTHFR activity, modifies the homocysteine plasma concentration and, among others, increases the risks for idiopathic male...
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