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Article

Exome sequencing in one family with gastric- and rectal cancer.

BMC genetics - 13 Feb 2016

Thutkawkorapin Jessada, Picelli Simone, Kontham Vinaykumar, Liu Tao, Nilsson Daniel, Lindblom Annika

Abstract excerpt

BACKGROUND: Heritable factors are well known to increase the risk of cancer in families. Known susceptibility genes account for a small proportion of all colorectal cancer cases. The aim of this study was to identify the genetic background in a family suggested to segregate a dominant cancer syndrome with a high risk of rectal- and gastric cancer. We performed whole exome sequencing in three family members, 2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26872740
DOI: 10.1186/s12863-016-0351-z
PMCID: PMC4752738

Genes

IGSF10
NOTCH1
SUCNR1
TRIOBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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