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KSHV Genome Replication and Maintenance

1 Feb 2016

Abstract excerpt

Kaposi's sarcoma associated herpesvirus (KSHV) or human herpesvirus 8 (HHV8) is a major etiological agent for multiple severe malignancies in immune-compromised patients. KSHV establishes lifetime persistence in the infected individuals and displays two distinct life cycles, generally a prolonged passive latent, and a short productive or lytic cycle. During latent phase, the viral episome is tethered to the host...

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Identifiers

PMID: 26870016
DOI: 10.3389/fmicb.2016.00054

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