Article
Kaposi’s Sarcoma-Associated Herpesvirus LANA Hitches a Ride on the Chromosome
8 May 2006
Abstract excerpt
Kaposi's sarcoma-associated herpesvirus (KSHV) latently infects tumor cells and has an etiologic role in Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease. Survival in rapidly dividing cells depends on a carefully orchestrated chain of events. The viral genome, or episome, must replicate in concert with cellular genetic material, and then efficiently segregate to progeny nuclei....
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