Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of Kaposi's sarcoma-associated herpesvirus LANA regions important for episome segregation, replication, and persistence.

Journal of virology - 1 Nov 2013

Vázquez Erika De León, Carey Vincent J, Kaye Kenneth M

Abstract excerpt

Kaposi's sarcoma-associated herpesvirus (KSHV) latency-associated nuclear antigen (LANA) is a 1,162-amino-acid protein that mediates the maintenance of episomal viral genomes in latently infected cells. The two central components of episome persistence are DNA replication with each cell division and the segregation of DNA to progeny nuclei. LANA self-associates to bind KSHV terminal-repeat (TR) DNA and to mediate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Viral
Share to DNA Replication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electrophoretic Mobility Shift Assay

Share to Half-Life

Share to Herpesvirus 8, Human

Share to Lymphoma, B-Cell

Share to Sarcoma, Kaposi

Share to Terminal Repeat Sequences

Source

Open in PubMed Open full text

Identifiers

PMID: 24006437
DOI: 10.1128/JVI.01243-13
PMCID: PMC3807934

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of Kaposi's sarcoma-associated herpesvirus LANA regions important for episome segregation, replication, and persistence.PMID 24006437Read ↗

The Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen 1 N terminus is essential for chromosome association, DNA replication, and episome persistence.Semantic proximity Read ↗

KSHV Genome Replication and MaintenanceSemantic proximity Read ↗

Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen 1 Mediates Episome Persistence through <i>cis</i> -Acting Terminal Repeat (TR) Sequence and Specifically Binds TR DNASemantic proximity Read ↗

Role of Kaposi's sarcoma-associated herpesvirus C-terminal LANA chromosome binding in episome persistence.Semantic proximity Read ↗

Analysis of Viral cis Elements Conferring Kaposi's Sarcoma-Associated Herpesvirus Episome Partitioning and MaintenanceSemantic proximity Read ↗

Kaposi’s Sarcoma Herpesvirus Genome PersistenceSemantic proximity Read ↗

Chromosome Binding Site of Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus Is Essential for Persistent Episome Maintenance and Is Functionally Replaced by Histone H1Semantic proximity Read ↗

The Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus Supports Latent DNA Replication in Dividing CellsSemantic proximity Read ↗

KSHV LANA—The Master Regulator of KSHV LatencySemantic proximity Read ↗

The Latency-Associated Nuclear Antigen, a Multifunctional Protein Central to Kaposi‘s Sarcoma-Associated Herpesvirus LatencySemantic proximity Read ↗

The Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus Permits Replication of Terminal Repeat-Containing PlasmidsSemantic proximity Read ↗

Kaposi’s Sarcoma-Associated Herpesvirus LANA Hitches a Ride on the ChromosomeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.