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Article

Estrogen, SNP-Dependent Chemokine Expression and Selective Estrogen Receptor Modulator Regulation.

Molecular endocrinology (Baltimore, Md.) - 1 Mar 2016

Ho Ming-Fen, Bongartz Tim, Liu Mohan, Kalari Krishna R, Goss Paul E, Shepherd Lois E, Goetz Matthew P, Kubo Michiaki, Ingle James N, Wang Liewei, Weinshilboum Richard M

Abstract excerpt

We previously reported, on the basis of a genome-wide association study for aromatase inhibitor-induced musculoskeletal symptoms, that single-nucleotide polymorphisms (SNPs) near the T-cell leukemia/lymphoma 1A (TCL1A) gene were associated with aromatase inhibitor-induced musculoskeletal pain and with estradiol (E2)-induced TCL1A expression. Furthermore, variation in TCL1A expression influenced the downstream...

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Identifiers

PMID: 26866883
DOI: 10.1210/me.2015-1267
PMCID: PMC4771694

Genes

CCR6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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