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Article

The Low-pH Resistance of Neuraminidase Is Essential for the Replication of Influenza A Virus in Duck Intestine following Infection via the Oral Route.

Journal of virology - 1 Apr 2016

Fujimoto Yoshikazu, Ito Hiroshi, Ono Etsuro, Kawaoka Yoshihiro, Ito Toshihiro

Abstract excerpt

UNLABELLED: Influenza A viruses are known to primarily replicate in duck intestine following infection via the oral route, but the specific role of neuraminidase (NA) for the intestinal tropism of influenza A viruses has been unclear. A reassortant virus (Dk78/Eng62N2) did not propagate in ducks infected via the oral route. To generate variant viruses that grow well in ducks via the oral route, we isolated...

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Source

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Identifiers

PMID: 26865722
DOI: 10.1128/JVI.03107-15
PMCID: PMC4810549

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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