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Article

Resistance mutation R292K is induced in influenza A(H6N2) virus by exposure of infected mallards to low levels of oseltamivir.

PloS one - 1 Jan 2013

Gillman Anna, Muradrasoli Shaman, Söderström Hanna, Nordh Johan, Bröjer Caroline, Lindberg Richard H, Latorre-Margalef Neus, Waldenström Jonas, Olsen Björn, Järhult Josef D

Abstract excerpt

Resistance to neuraminidase inhibitors (NAIs) is problematic as these drugs constitute the major treatment option for severe influenza. Extensive use of the NAI oseltamivir (Tamiflu®) results in up to 865 ng/L of its active metabolite oseltamivir carboxylate (OC) in river water. There one of the natural reservoirs of influenza A, dabbling ducks, can be exposed. We previously demonstrated that an influenza A(H1N1)...

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Identifiers

PMID: 23951116
DOI: 10.1371/journal.pone.0071230
PMCID: PMC3741332

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Resistance mutation R292K is induced in influenza A(H6N2) virus by exposure of infected mallards to low levels of oseltamivir.PMID 23951116Read ↗

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