Article
Intake of Total and Subgroups of Fat Minimally Affect the Associations between Selected Single Nucleotide Polymorphisms in the PPARγ Pathway and Changes in Anthropometry among European Adults from Cohorts of the DiOGenes Study.
The Journal of nutrition - 1 Mar 2016
Larsen Sofus C, Ängquist Lars, Østergaard Jane N, Ahluwalia Tarunveer S, Vimaleswaran Karani S, Roswall Nina, Mortensen Lotte M, Nielsen Birgit M, Tjønneland Anne, Wareham Nicholas J, Palli Domenico, Masala Giovanna, Saris Wim H M, van der A Daphne L, Boer Jolanda M A, Feskens Edith J M, Boeing Heiner, Jakobsen Marianne U, Loos Ruth J F, Sørensen Thorkild I A, Overvad Kim
Abstract excerpt
BACKGROUND: Although the peroxisome proliferator-activated receptor γ (PPARγ) pathway is central in adipogenesis, it remains unknown whether it influences change in body weight (BW) and whether dietary fat has a modifying effect on the association. OBJECTIVES: We examined whether 27 single nucleotide polymorphisms (SNPs) within 4 genes in the PPARγ pathway are associated with the OR of being a BW gainer or with...
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