Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction of NOS1AP with the NOS-I PDZ domain: Implications for schizophrenia-related alterations in dendritic morphology.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Apr 2016

Candemir Esin, Kollert Leonie, Weißflog Lena, Geis Maria, Müller Antje, Post Antonia M, O'Leary Aet, Harro Jaanus, Reif Andreas, Freudenberg Florian

Abstract excerpt

Schizophrenia involves morphological brain changes, including changes in synaptic plasticity and altered dendritic development. Amongst the most promising candidate molecules for schizophrenia are neuronal nitric oxide (NO) synthase (NOS-I, also known as nNOS) and its adapter protein NOS1AP (previously named CAPON). However, the precise molecular mechanisms by which NOS-I and NOS1AP affect disease pathology...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Cerebral Cortex

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dendritic Spines

Share to Hippocampus

Share to Nitric Oxide Synthase Type I

Share to Primary Cell Culture

Share to Protein Binding

Share to Schizophrenia

Source

Identifiers

PMID: 26861996
DOI: 10.1016/j.euroneuro.2016.01.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction of NOS1AP with the NOS-I PDZ domain: Implications for schizophrenia-related alterations in dendritic morphology.PMID 26861996Read ↗

NOS1AP regulates dendrite patterning of hippocampal neurons through a carboxypeptidase E-mediated pathway.Semantic proximity Read ↗

Nitric oxide synthase 1 adaptor protein, a protein implicated in schizophrenia, controls radial migration of cortical neurons.Semantic proximity Read ↗

Unexpected Heterodivalent Recruitment of NOS1AP to nNOS Reveals Multiple Sites for Pharmacological Intervention in Neuronal Disease Models.Semantic proximity Read ↗

The genetic contribution of the NO system at the glutamatergic post-synapse to schizophrenia: further evidence and meta-analysis.Semantic proximity Read ↗

NOS1AP in schizophrenia.Semantic proximity Read ↗

Morphological and transcriptomic analyses of stem cell-derived cortical neurons reveal mechanisms underlying synaptic dysfunction in schizophreniaSemantic proximity Read ↗

Identification of a psychiatric risk gene NISCH at 3p21.1 GWAS locus mediating dendritic spine morphogenesis and cognitive function.Semantic proximity Read ↗

Dendritic structural plasticity and neuropsychiatric disease.Semantic proximity Read ↗

Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex.Semantic proximity Read ↗

Decoding spine nanostructure in cultured neurons derived from mouse models of neuropsychiatric disorder reveals a schizophrenia-linked role for Ecrg4Semantic proximity Read ↗

Reversal of dendritic phenotypes in 16p11.2 microduplication mouse model neurons by pharmacological targeting of a network hub.Semantic proximity Read ↗

Control of interneuron dendritic growth through NRG1/erbB4-mediated kalirin-7 disinhibition.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.