Article
Expression of area-specific M2-macrophage phenotype by recruited rat monocytes in duct-ligation pancreatitis.
Histochemistry and cell biology - 1 Jun 2016
Yu Enqiao, Goto Mataro, Ueta Hisashi, Kitazawa Yusuke, Sawanobori Yasushi, Kariya Taro, Sasaki Masaru, Matsuno Kenjiro
Abstract excerpt
Acute pancreatitis remains a disease of uncertain pathogenesis and no established specific therapy. Previously, we found a predominant increase and active proliferation of macrophages in the inflamed tissues of a rat duct-ligation pancreatitis model. To analyze the origin and possible role of these macrophages, we investigated their in situ cellular kinetics in a rat model of duct-ligation pancreatitis using a...
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