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Article

A RelA(p65) Thr505 phospho-site mutation reveals an important mechanism regulating NF-κB-dependent liver regeneration and cancer.

Oncogene - 1 Sept 2016

Moles A, Butterworth J A, Sanchez A, Hunter J E, Leslie J, Sellier H, Tiniakos D, Cockell S J, Mann D A, Oakley F, Perkins N D

Abstract excerpt

Post-translational modifications of nuclear factor (NF)-κB subunits provide a mechanism to differentially regulate their activity in response to the many stimuli that induce this pathway. However, the physiological significance of these modifications is largely unknown, and it remains unclear if these have a critical role in the normal and pathological functions of NF-κB in vivo. Among these, phosphorylation of...

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Identifiers

PMID: 26853469
DOI: 10.1038/onc.2015.526
PMCID: PMC4862573

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A RelA(p65) Thr505 phospho-site mutation reveals an important mechanism regulating NF-κB-dependent liver regeneration and cancer.PMID 26853469Read ↗

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