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Article

Fracture Healing Is Delayed in Immunodeficient NOD/scid‑IL2Rγcnull Mice.

PloS one - 1 Jan 2016

Rapp Anna E, Bindl Ronny, Recknagel Stefan, Erbacher Annika, Müller Ingo, Schrezenmeier Hubert, Ehrnthaller Christian, Gebhard Florian, Ignatius Anita

Abstract excerpt

Following bone fracture, the repair process starts with an inflammatory reaction at the fracture site. Fracture healing is disturbed when the initial inflammation is increased or prolonged, whereby, a balanced inflammatory response is anticipated to be crucial for fracture healing, because it may induce down-stream responses leading to tissue repair. However, the impact of the immune response on fracture healing...

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Identifiers

PMID: 26849055
DOI: 10.1371/journal.pone.0147465
PMCID: PMC4744061

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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