Article
A Pronounced Inflammatory Activity Characterizes the Early Fracture Healing Phase in Immunologically Restricted Patients.
International journal of molecular sciences - 8 Mar 2017
Hoff Paula, Gaber Timo, Strehl Cindy, Jakstadt Manuela, Hoff Holger, Schmidt-Bleek Katharina, Lang Annemarie, Röhner Eric, Huscher Dörte, Matziolis Georg, Burmester Gerd-Rüdiger, Schmidmaier Gerhard, Perka Carsten, Duda Georg N, Buttgereit Frank
Abstract excerpt
Immunologically restricted patients such as those with autoimmune diseases or malignancies often suffer from delayed or insufficient fracture healing. In human fracture hematomas and the surrounding bone marrow obtained from immunologically restricted patients, we analyzed the initial inflammatory phase on cellular and humoral level via flow cytometry and multiplex suspension array. Compared with controls, we...
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