Article
Genetic Variant in ACVR2B Is Associated with Lean Mass.
Medicine and science in sports and exercise - 1 Jul 2016
Klimentidis Yann C, Bea Jennifer W, Thompson Patricia, Klimecki Walter T, Hu Chengcheng, Wu Guanglin, Nicholas J Skye, Ryckman Kelli K, Chen Zhao
Abstract excerpt
INTRODUCTION: Low lean mass (LM) is a risk factor for chronic disease, a major cause of disability and diminished quality of life, and is a heritable trait. However, relatively few specific genetic factors have been identified as potentially influencing this trait. METHODS: In this study, we selected 1493 single-nucleotide polymorphisms (SNP) in 155 candidate genes involved in anabolic, catabolic, growth hormone,...
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