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Article

Activin-type II receptor B (<i>ACVR2B</i>) and <i>follistatin</i> haplotype associations with muscle mass and strength in humans

9 Mar 2007

Abstract excerpt

Genetic variation in myostatin, a negative regulator of skeletal muscle, in cattle has shown remarkable influence on skeletal muscle, resulting in a double-muscled phenotype in certain breeds; however, DNA sequence variation within this gene in humans has not been consistently associated with skeletal muscle mass or strength. Follistatin and activin-type II receptor B (ACVR2B) are two myostatin-related genes...

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PMID: 17347381
DOI: 10.1152/japplphysiol.01322.2006

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