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Article

Fanconi anemia genes in lung adenocarcinoma- a pathway-wide study on cancer susceptibility.

Journal of biomedical science - 3 Feb 2016

Yang Shi-Yi, Hsiung Chia-Ni, Li Yao-Jen, Chang Gee-Chen, Tsai Ying-Huang, Chen Kuan-Yu, Huang Ming-Shyan, Su Wu-Chou, Chen Yuh-Min, Hsiung Chao A, Yang Pan-Chyr, Chen Chien-Jen, Wu Pei-Ei, Yu Jyh-Cherng, Shen Chen-Yang, Hsu Huan-Ming

Abstract excerpt

BACKGROUND: Carcinogens in cigarette smoke can induce the formation of DNA-DNA cross-links, which are repaired by the Fanconi anemia (FA) pathway, and it is tempting to speculate that this pathway is involved in lung tumorigenesis. This study is to determine whether genetic polymorphism of the FA genes is associated with an elevated risk of lung adenocarcinoma, and whether the association between genotypes and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26842001
DOI: 10.1186/s12929-016-0240-9
PMCID: PMC4739091

Genes

FANCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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