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Article

Association of RAC1 Gene Polymorphisms with Primary End-Stage Renal Disease in Chinese Renal Recipients.

PloS one - 1 Jan 2016

Liu Yani, Zhou Jiali, Luo Xiaomei, Yang Chunxiao, Zhang Yu, Shi Shaojun

Abstract excerpt

BACKGROUND/OBJECTIVE: RAC1 gene could influence susceptibility to renal failure by altering the activity and expression of Rac1, which is a member of the Rho family of small GTP-binding proteins. In clinical practice, renal transplantation provides the optimal treatment for people with end-stage renal disease (ESRD). The objective of this present study was to determine whether the RAC1 gene polymorphisms were...

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Source

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Identifiers

PMID: 26841219
DOI: 10.1371/journal.pone.0148270
PMCID: PMC4739498

Genes

RAC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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