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Article

PHOX2B is a suppressor of neuroblastoma metastasis.

Oncotarget - 1 Mar 2016

Naftali Osnat, Maman Shelly, Meshel Tsipi, Sagi-Assif Orit, Ginat Ravit, Witz Isaac P

Abstract excerpt

Paired like homeobox 2B (PHOX2B) is a minimal residual disease (MRD) marker of neuroblastoma. The presence of MRD, also referred to as micro-metastases, is a powerful marker of poor prognosis in neuroblastoma. Lung metastasis is considered a terminal event in neuroblastoma. Lung micro-metastatic neuroblastoma (MicroNB) cells show high expression levels of PHOX2B and possess a less malignant and metastatic...

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Source

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Identifiers

PMID: 26840262
DOI: 10.18632/oncotarget.7056
PMCID: PMC4891146

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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