Article
MicroRNA-23a promotes neuroblastoma cell metastasis by targeting CDH1
14 Jan 2014
Abstract excerpt
CDH1 inactivation is important in tumor metastasis. In the present study, it was suggested that the mRNA and protein levels of CDH1 decreased in metastatic neuroblastoma (NB) tissues compared with those in primary NB tissues. The aim of the study was to explore the regulatory mechanisms of CDH1 downregulation in metastatic NB. MicroRNAs are small non‑coding RNAs (~22 nt in length) that negatively regulate target...
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